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Goserelin (Goserelin Acetate)

= Prescription Required   = Generic Equvalent

Zoladex
3.6mg Kit
Goserelin (Goserelin Acetate)
Zoladex
10.8mg Kit
Goserelin (Goserelin Acetate)

Goserelin (Goserelin Acetate) Prescription Drug Information

Goserelin (Injection)
Goserelin (goe-se-REL-in)

Treats prostate cancer and breast cancer. In women, also used to treat endometriosis and to make the lining of the uterus thin before surgery.

Brand Name(s):Zoladex
There may be other brand names for Goserelin (Goserelin Acetate).

When Goserelin (Goserelin Acetate) Should Not Be Used:
You should not receive Goserelin (Goserelin Acetate) if you have had an allergic reaction to goserelin or similar medicines such as gonadorelin, Factrel®, or LHRH. For a woman, you should not use Goserelin (Goserelin Acetate) if you are pregnant or have unusual vaginal bleeding that has not been checked by a doctor.

How to Use Goserelin (Goserelin Acetate):
Injectable

  • You will receive Goserelin (Goserelin Acetate) while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you Goserelin (Goserelin Acetate).
  • Your doctor will prescribe your exact dose and tell you how often it should be given. Goserelin (Goserelin Acetate) is given as a shot under your skin near your stomach. Goserelin (Goserelin Acetate) may be given once every 28 days or once every 3 months. Your schedule depends on the reason you are using Goserelin (Goserelin Acetate).

If a dose of Goserelin (Goserelin Acetate) is missed:

  • Goserelin (Goserelin Acetate) needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Drugs and Foods to Avoid While Taking Goserelin (Goserelin Acetate):
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using other hormone medicines (such as Pregnyl®, Profasi®), a steroid medicine (such as cortisone, prednisone, or Medrol®), or medicine for seizures (such as phenytoin, Depakote®, or Dilantin®).
  • Birth control pills, implants, patches, or shots may not work while you are using Zoladex®. To keep from getting pregnant, use another form of birth control together with your pills. Other forms include condoms, a diaphragm, or contraceptive foam or jelly.

Warnings While Using Goserelin (Goserelin Acetate):

  • For women: Using Goserelin (Goserelin Acetate) while you are pregnant may harm your unborn baby. Your birth control pills may not work as well while you are receiving Goserelin (Goserelin Acetate). Use a nonhormonal form of birth control together with your pills to keep from getting pregnant while you are receiving Goserelin (Goserelin Acetate) and for at least 12 weeks after treatment. Nonhormonal birth control includes vaginal spermicides, condoms, diaphragms, and cervical caps. If you think you have become pregnant while using the medicine, tell your doctor right away.
  • Make sure your doctor knows if you are breastfeeding or have bone cancer, diabetes, spinal cord (back) problems, trouble urinating, blood pressure problems, or pituitary gland problems.
  • For women: You will stop having menstrual periods while you are using Goserelin (Goserelin Acetate). This is not an effective form of birth control. If you keep having normal periods while using Goserelin (Goserelin Acetate), tell your doctor. If your periods do not return to normal after you stop using Goserelin (Goserelin Acetate), tell your doctor.
  • For male patients: Goserelin (Goserelin Acetate) may affect blood sugar levels. If you are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.
  • When you first start using Goserelin (Goserelin Acetate) for cancer treatment, some of your symptoms might get worse for a short time. You might also have new symptoms. You might have bone pain, back pain, or trouble urinating. These symptoms should improve within a few weeks. Tell your doctor if you have any new symptoms or your symptoms get worse.
  • Goserelin (Goserelin Acetate) might cause you to lose some bone density. Tell your doctor if you have risk factors for osteoporosis (thin or brittle bones). Some risk factors are alcohol abuse, tobacco cigarette smoking, a family history of osteoporosis, or using other medicines that might cause bone density loss, such as steroids or medicine for seizures.
  • Goserelin (Goserelin Acetate) may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are using Goserelin (Goserelin Acetate).
  • Make sure any doctor or dentist who treats you knows that you are using Goserelin (Goserelin Acetate). Goserelin (Goserelin Acetate) may affect the results of certain medical tests.
  • Your doctor will need to check your progress at regular visits while you are using Goserelin (Goserelin Acetate). Be sure to keep all appointments.

Possible Side Effects While Using Goserelin (Goserelin Acetate):
Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
  • Black, tarry stools.
  • Bloody or cloudy urine, or painful urination.
  • Change in how much or how often you urinate.
  • Fever, chills, cough, sore throat, and body aches.
  • Lightheadedness or fainting.
  • Swelling in your hands or feet.

If you notice these less serious side effects while taking Goserelin (Goserelin Acetate), talk with your doctor:

  • Back pain.
  • Dryness or itching in your vagina.
  • Headache, mood changes, mild depression, or unusual tiredness.
  • Hot flashes, sweating, or change in breast size.
  • Mild nausea, vomiting, diarrhea, loss of appetite, or stomach pain.
  • Pain, itching, burning, swelling, or a lump under your skin where the shot was given.
  • Skin rash.
  • Trouble having sex or loss of interest in sex.
  • Trouble with sleeping.

If you notice other side effects that you think are caused by Goserelin (Goserelin Acetate), tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

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Winnipeg MB  R3N 1Z4
Canada

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