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 = Prescription Required
 = Generic Equvalent
Amylase/Lipase/Protease
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Cotazym
30K-8K-30K Capsules
Amylase/Lipase/Protease
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Cotazym E.C.S. 8
30-8-30 Bolus
Amylase/Lipase/Protease
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Pancrease MT 16
48-16-48 Capsules (Enteric-Coated)
Amylase/Lipase/Protease
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Pancrease MT 4
12K-4K-12K Capsules (Enteric-Coated)
Amylase/Lipase/Protease
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Amylase/Lipase/Protease Information
Pancrelipase (By mouth)
Amylase (AM-i-lase), Lipase (LYE-pase), Protease (PROE-tee-ase)
An enzyme that helps digest foods for patients who have cystic fibrosis and digestive disorders.
Brand Name(s):Creon 10, Creon 20, Viokase, Viokase 16, Lipram-Pn20, Lipram-Pn16, Lipram 4500, Lipram-Pn10, Ultrase Mt20, Pancrease MT 4, Lapase, Dygase, Pancrease, Ultrase, Pangestyme EC
There may be other brand names for Amylase/Lipase/Protease. When Amylase/Lipase/Protease Should Not Be Used:
You should not use Amylase/Lipase/Protease if you have had an allergic reaction to pancrelipase, pancreatin, or pork products. How to Use Amylase/Lipase/Protease:
Capsule, Delayed Release Capsule, Long Acting Capsule, Powder, Tablet, Coated Tablet
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Your doctor will tell you how much of Amylase/Lipase/Protease to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.
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Drink a full glass of water with your medicine and plenty of fluids during the day.
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Take Amylase/Lipase/Protease with meals and snacks as directed by your doctor.
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If the capsule opens, keep the powder away from your nose to avoid breathing in the powder. It can be very irritating to your lungs.
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Swallow the capsule or tablet whole. Do not let it dissolve in your mouth.
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Do not chew or crush the delayed-released capsule. Swallow it whole. If the capsule is too big to swallow, open it and put the contents in soft food (such as applesauce, pureed bananas or pears). Swallow the mixture right away without crushing or chewing it. Do not mix the capsule with alkaline foods or liquids, such as milk, breast milk, or formula.
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When the delayed-released capsule is given to infants, the contents of the capsule may be put directly into the mouth or mixed with a small amount of soft food (such as applesauce, pureed bananas or pears) and given before each feeding.
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Take the powder with meals. Keep the powder away from your nose to avoid breathing in the powder. It can be very irritating to your lungs.
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Amylase/Lipase/Protease should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions. Ask your pharmacist for the Medication Guide if you do not have one. Your doctor might ask you to sign some forms to show that you understand this information.
If a dose is missed:
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If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of Amylase/Lipase/Protease:
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Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
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Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
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Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
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Make sure your doctor knows if you are taking iron supplements or vitamins that contain iron.
Warnings While Using Amylase/Lipase/Protease:
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Make sure your doctor knows if you are pregnant or breastfeeding, or if you have severe pancreas disease, kidney problems, gout, hyperuricemia (high uric acid in the blood), or a bowel problem called fibrosing colonopathy (blocked intestines, or a scarred or thick bowel wall). Tell your doctor if you have trouble swallowing capsules.
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Amylase/Lipase/Protease is made from the pancreas of pigs. The risk of getting a virus from medicines made of pig organs has been greatly reduced in recent years. This is the result of required testing for certain viruses, and testing during manufacture of these medicines. Although the risk of transmitting certain viruses to people who will use the medicine is low, talk with your doctor if you have concerns.
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Your doctor will need to check your progress at regular visits while you are using Amylase/Lipase/Protease. Be sure to keep all appointments.
Possible Side Effects While Using Amylase/Lipase/Protease:
Call your doctor right away if you notice any of these side effects:
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Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing.
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Joint pain or swelling.
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Severe stomach pain.
If you notice these less serious side effects, talk with your doctor:
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Cough.
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Diarrhea, constipation, nausea, vomiting, or gas.
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Dizziness.
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Headache.
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Stomach upset or cramps.
If you notice other side effects that you think are caused by Amylase/Lipase/Protease, tell your doctor.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088
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